First US baby from a uterus transplant is born in Dallas: New mom delivered screaming healthy infant via c-section after receiving womb from a mother-of-two nurse who lives nearby
- The woman, who was not identified, gave birth to a baby at Baylor University Medical Center in Dallas
- It is not clear what day the baby was born, or what is the baby's gender
- The birth announcement comes a year after Baylor announced it had performed four womb transplants, but three had to be removed due to poor blood flow?
- On Friday, Baylor released photos of the team delivering the baby via cesarean section
- The donor is a registered nurse in Dallas called Taylor Siler, 36, who decided to donate her uterus after having two children of her own, now aged four and six years old?
The first birth as a result of a womb transplant in the United States has occurred in Texas, marking a milestone for American medicine.
A woman who had been born without a uterus gave birth to the baby at Baylor University Medical Center in Dallas about a year after receiving a womb from a 36-year-old mother-of-two nurse who lives near the hospital.
Hospital spokesman Craig Civale confirmed on Friday that the birth had taken place, but said no other details are available.?
The hospital did not identify the woman, citing her privacy.
The breakthrough comes after years of attempts by various hospitals to perfect the art of womb transplants, which has only been a success in Sweden. The Cleveland Clinic in Ohio made headlines in early 2016 after transplanting a deceased donor's womb into a patient, but it had to be removed days later due to a yeast infection.?
In October 2016, Baylor quietly announced it had performed four uterus transplants using living donors - the same approach as the Swedish team. Though three had to be removed due to poor blood flow, one was a success.?
This is the first American baby born after a uterus transplant in?Baylor University Medical Center in Dallas. Pictured:?Dr Robert T. Gunby Jr holds up the baby to show the mother
The baby's birth was announced on Friday, a year after Baylor performed four womb transplants
The woman and her husband have not been identified
HOW IS A WOMB TRANSPLANT PERFORMED??
The first step involves doctors removing some of the patients' eggs in order to fertilize them in a dish to create embryos.
These are then frozen, until they are needed.
Secondly, a womb, complete with two major arteries and four veins, removed from a from donor in a three-hour operation.
The donated womb is then implanted into the patient during an operation that typically takes around six hours.
The woman is then, as all organ transplant patients are, prescribed powerful immune-suppressing drugs to stop the transplanted womb being rejected by the body.
Around a year later, when doctors are confident the transplant is a success, one of the embryos is thawed and implanted into the donated womb.
If the pregnancy is a success, doctors ultimately deliver the baby via C-section.
Once a woman has successfully carried one or two babies, the transplanted organ is then removed.
Baylor has had a study underway for several years to enroll up to 10 women for uterus transplants.?
In October 2016, the hospital said four women had received transplants but that three of the wombs had to be removed because of poor blood flow.
The hospital would give no further information on how many transplants have been performed since then.?
But Time magazine, which first reported the US baby's birth, says eight have been done in all, and that another woman is currently pregnant as a result.?
The first four cases involved 'altruistic' donors — unrelated and unknown to the recipients. The ones done in Sweden were from live donors, mostly from the recipients' mother or a sister.
While little is known about the new mother, Time spoke to her donor Taylor Siler, 36, who is a registered nurse and mother-of-two in Dallas.?
'I have family members who struggled to have babies, and it's not fair,' Siler told the newspaper. 'I just think that if we can give more people that option, that's an awesome thing.'?
A doctor in Sweden, Mats Brannstrom, is the first in the world to deliver a baby as a result of a uterus transplant. As of last year, he had delivered five babies from women with donated wombs.
There have been at least 16 uterus transplants worldwide, including one in Cleveland from a deceased donor that had to be removed because of complications. Last month, Penn Medicine in Philadelphia announced that it also would start offering womb transplants.
Womb donors can be dead or alive, and the Baylor study aims to use some of both.??
Doctors hope that womb transplants will enable as many as several thousand women born without a uterus to bear children.?
To be eligible for the Baylor study, women must be 20 to 35 years old and have healthy, normal ovaries. They will first have in vitro fertilization to retrieve and fertilize their eggs and produce embryos that can be frozen until they are ready to attempt pregnancy.
After the uterus transplant, the embryos can be thawed and implanted, at least a year after the transplant to make sure the womb is working well.?
A baby resulting from a uterine transplant would be delivered by cesarean section.?
The wombs are not intended to be permanent.?
Having one means a woman must take powerful drugs to prevent organ rejection, and the drugs pose long-term health risks, so the uterus would be removed after one or two successful pregnancies.
The American Society for Reproductive Medicine issued a statement Friday calling the Dallas birth 'another important milestone in the history of reproductive medicine.'
For women born without a functioning uterus, 'transplantation represents the only way they can carry a pregnancy,' the statement said. The group is convening experts to develop guidelines for programs that want to offer this service.
KEY QUESTIONS OVER AMERICA'S WOMB TRANSPLANTS?
Why the excitement?
Experts in Sweden announced in 2015 that a baby boy had become the first in the world to be delivered following a successful womb transplant.?
The UK and US have now been racing to catch up. ?
How do women come to have no womb?
Thousands of women of child-bearing age in the US have no womb or a womb that would be unable to carry a baby.?
Some women are born with a syndrome known as MRKH (Mayer-Rokitansky-Kuster-Hauser), which means their womb never developed properly.?
Others lose their wombs to cervical cancer.
Data suggests as many as 50,000 women of childbearing age in the UK have no viable womb, and thousands in the US will be suffering the same condition.
Is it risky?
The operation takes around six hours, with the organ coming from a donor who has died but whose heart has been kept beating.
The recipient will need to take immune-suppressing drugs following the transplant and throughout any pregnancy to prevent the chance their body might reject the donor organ.
Once the donor womb is no longer needed, it can be removed by a team of surgeons. This would prevent the need for the woman to be on immune-suppressing drugs for the rest of her life.
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